The ingenious idea of using carbon dioxide to promote the transfer of oxygen within the human body to treat an area where carbon dioxide is present was made famous by the Danish physiologist Christian Bohr. This physiological phenomenon ﬁrst reported in 1904 became known today as the “Bohr Effect.” The Bohr effect is a normal process in people of normal health. It is the duality of how carbon dioxide and oxygen work harmoniously with one another. With the Bohr effect, it is understood that carbon dioxide is the key factor which triggers our own body for the transport and release of oxygen through our red blood cells. As a result, when carbon dioxide is present at the location being treated, our own body will send oxygen through the process of vasodilation to that location of treatment.
The initial uses in Europe were used as a naturopathic method in the form of injections. The physiological effects of carbon dioxide were made popular initially in Europe where carbon dioxide spring was used for medical treatment. The purpose of using this treatment as an injection was speciﬁcally designed to create a natural vasodilator. This will cause the blood vessels to widen for the improvement of blood ﬂow and as a result increase the transport of oxygen to various tissues for cellular regeneration as well as act as an anti-inﬂammatory.
The Development of a Non-Injectable Version in Japan:
With the years of successful studies and results in Europe, Japan has taken the treatment’s principle a step further in enabling the same powerful results, but without the use of injections. After many years of trials with different formulations, they have effectively created a solution to provide the same powerful results without the use of needles.
The Evolution into an Aesthetic/Anti-Aging Product:
This non-injectable treatment was originally created in Japan for the use at hospitals to treat burn victims and for wound healing due to its physiological effects. For each successful outcome reported, several patients with burns or wounds to the face began to notice additional beneﬁcial effects from this treatment. The results were astonishing. Not only did the patient’s primary wounds and burns heal, the patients visually experienced improvements to the texture of their skin. In addition, patients experienced reduction in ﬁne lines and wrinkles, reduction in the size of their pores, as well as a more ﬁrm and lifted appearance to their face. These results contributed greatly to the birth of a powerful aesthetic/anti-aging treatment.